LO 6.1: I can explain how the molecule of life replicates.
Lesson 6.1 Gene Expression (Day 1)
Do Now: What does it mean that DNA replication is a Semi-Conservative Model?
DNA replication is a Semi-Conservative Model because it preserves half the original DNA and stores the new DNA between the original DNA.
DNA Helicase Helicase is the first step of DNA replication and unzips the DNA helix into individual strands to create a replication fork.
DNA Topoisomerase Topoisomerase keeps track of the unzipped DNA.
DNA Primase Primase is the second step of DNA replication and makes an RNA primer that anneals, starting the replication process. It is 5-10 nucleotides long.
DNA Polymerase III DNA polymerase III is the third step of DNA replication attaches to DNA strands and copies new strands. This connects the phosphate group of each nucleotide. The strands are antiparallel, so the stands must be in opposite directions. Polymerase follows helicase and synthesizes a continuous strand of DNA.
Okazaki Fragment Okazaki Fragment is 100-200 nucleotides long and lagging strands.
DNA Polymerase I DNA Polymerase is the fourth step of DNA replication and replaces the RNA primers with DNA nucleotides.
DNA Ligase Ligase is the fifth of DNA replication will go through the process and reseals the DNA strand.